<b>COMPARISON OF SEROTONIN-PRODUCING MURINE MASTOCYTOMAS, P-815 AND FMA3: DETERMINATION OF TRYPTOPHAN HYDROXYLASE, AROMATIC L-AMINO ACID DECARBOXYLASE, AND CELLULAR CONCENTRATION OF TRYPTOPHAN, 5-HYDROXYTRYPTOPHAN, 5-HYDROXYTRYPTAMINE AND 5-HYDROXYINDOLEACETIC </b><b>ACID </b>
نویسندگان
چکیده
منابع مشابه
On the identity of DOPA decarboxylase and 5-hydroxytryptophan decarboxylase (immunological titration-aromatic L-amino acid decarboxylase-serotonin-dopamine-norepinephrine).
Simultaneous immunological titration of DOPA and 5-hydroxytryptophan decarboxylase activities, from a number of tissues of various species, showed that the two activities were not distinguishable with a monospecific antiserum to hog kidney decarboxylase. Together with previous findings, these data firmly establish the concept that in mammalian tissues the two enzyme activities are associated wi...
متن کاملTryptophan and 5-hydroxytryptophan for depression.
BACKGROUND 5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. OBJECTIVES To determine whether 5-HTP and tryptophan are more effective than placebo, and whether they are safe to use to treat depressive disorders in adults. SEARCH STRATEGY Trials were searched in computerized general (M...
متن کاملUrinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects.
Urinary 5-hydroxyindoleacetic acid (5-HIAA) excretion in two consecutive collection periods (5:00 PM-11:00 PM and 11:00 PM-8:00 AM) and whole blood serotonin (5-HT) and tryptophan (TRP) were measured in groups of unmedicated autistics (n = 16), medicated autistics (n = 20), and normal controls (n = 27). Whole blood 5-HT values were significantly higher in unmedicated autistics compared to norma...
متن کاملAutoantibodies to human tryptophan hydroxylase and aromatic L-amino acid decarboxylase.
OBJECTIVE To assess the prevalence of autoantibodies (Abs) to tryptophan hydroxylase (TPH) and aromatic l-amino acid decarboxylase (AADC) in patients with different autoimmune diseases and to analyse their respective epitopes. DESIGN TPH and AADC Abs were measured in an immunoprecipitation assay using (35)S-labelled full-length and fragments of TPH and AADC. METHODS Patients with different ...
متن کاملA simple determination of serotonin, 5-hydroxyindoleacetic acid and 5-hydroxytryptophan decarboxylase activity in rat brain areas and parallel correlation among the levels.
We devised a simple method for the separation of serotonin (5HT) and 5-hydroxyindoleacetic acid (5HIAA) using small P-cellulose and DEAE-Sephadex columns, respectively. Both substances were estimated fluorometrically by the reaction with o-phthalaldehyde (OPA). In this method, some known interfering substances in addition to many primary amines and amino acids were separated from 5HT and 5HIAA....
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1984
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.5.19